Tranexamic Acid was originally used to prevent excess bleeding in Menstrual bleeding , Haemophilia or Cardiac surgery. Later on, doctors discover great benefit in using Tranexamic Acid as an intradermal microinjection for Treatment of Melasma. It has become instantly popular amongst women who suffer from hyper pigmentation and skin discolorations to get their dosage of “whitening shots” on regular basis.
Tranexamic acid (TA) On Pigmentation Applied Topically
Kondou et al. have published results from a clinical study examining the effects of a tranexamic acid (TA) emulsion applied topically to melasma and freckles.1 The study involved 33 subjects, 25 with melasma and 8 with freckles, who applied the TA emulsion for five to eighteen weeks, after which their skin pigmentation was visually assessed by a dermatologist.
Researchers found that the TA emulsion had improved the pigmentation in 20 subjects with melasma (80%) and 6 subjects (75%) with freckles. No side effect was recognized and thus the TA emulsion was deemed safe. In regard to changes over the course of the study, marked improvement was observed within eight weeks for melasma but within 12 weeks for freckles; therefore, improvement was considered to require at least two months of topical application. The authors concluded the TA emulsion was an effective cosmeceutical that provided a whitening effect on melasma and freckles through inhibition of melanin synthesis. It also prevented the appearance of new pigment spots and freckles.
In 2006, UNT has introduced its newest whitening serum EX-White which uses Tranexamic Acid topically. At 3% concentration, EX-White can inhibit the growth of tyrosine and the activity level of melanin, starting to chip away the pigmentation from the edge inwards.
Tranexamic Acid is stable, not easily sabotaged by shift in temperature, not UV sensitive and will not oxidized easily. It is designed most suitable for users with hyper pigmentation.
Tranexamic Acid not only is the skincare of choice for pigmentation, but also the most effective ingredients thus far for getting ride of discoloration caused by acne and sun damage. During the life of an acne, your skin is under constant inflammation, which activate the growth of melanin. Tests show Tranexamic Acid can reduce melanin caused by inflammation by 32% and even out skin tone.
